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Decoding Breath · Research Review

Is the Wim Hof Method Safe, and Does It Really Do What People Claim

· 14:09 · By Jesse Coomer

The question: Is the Wim Hof Method safe, and does it really do what people claim?

The short answer: In the landmark 2014 Kox study, trained Wim Hof practitioners raised their adrenaline and blunted the short-term inflammatory response to a bacterial endotoxin, but a follow-up from the same lab traced that effect mostly to the cyclic hyperventilation phase, not a unique combination of the method's three pillars. The hyperventilation that drives the effect also carries real risks, including blackout and drowning when breath holds are done in or near water. Most popular long-term health claims run ahead of the evidence.

What the study did

The Wim Hof Method combines rapid deep breathing (typically 30 to 40 breaths, then a breath hold and a recovery breath), cold exposure and a mindset component. In the 2014 Kox study, published in PNAS, 12 practitioners trained in the full method and 12 untrained controls were injected with a bacterial endotoxin, a purified fragment of dead E. coli called lipopolysaccharide (LPS). It cannot replicate or cause an infection, but it triggers a standardized inflammatory response. The trained group used the breathing technique during the exposure. Because they were trained in all three components together, the study could not say which ingredient did the work. A follow-up from the same lab took the components apart.

What it found

Compared with controls, the trained group showed significantly higher epinephrine (adrenaline), lower pro-inflammatory cytokines and fewer flu-like symptoms. It was the first study to show that humans could voluntarily influence the innate immune response, which had been considered involuntary. The follow-up found that the sympathetic activation and the anti-inflammatory effect appeared to come mostly from the cyclic hyperventilation and the stress response it produces, not from the synergy of the three pillars. Jesse Coomer describes this as one instance of a general mechanism: voluntary hyperventilation triggers a large adrenaline surge that dampens the immune response. Other research reports increased epinephrine during the breathing, mood and stress improvements in some studies, and more brown fat activity in practitioners, likely more from cold than breathing.

What it doesn’t show

There was no live pathogen, virus or infection in the Kox study, so it does not show that the method kills bacteria, fights viral infections, speeds recovery from colds, treats cancer or cures autoimmune disease. The effect was short term and in a controlled lab setting. Claims about treating depression or PTSD, extending lifespan or outperforming standard exercise for cardiovascular fitness are not supported at the same level of evidence. The findings also do not show that the method does something no other practice producing a similar adrenaline response could do.

Key points

  • The Kox 2014 study showed trained practitioners could blunt the short-term inflammatory response to an inert bacterial fragment, not fight a real infection.
  • A follow-up from the same lab linked the effect mainly to cyclic hyperventilation, not to a unique synergy of breathing, cold and mindset.
  • Hyperventilating before breath holds delays the urge to breathe, which has led to blackout and drowning deaths in water.

Common questions

Why is Wim Hof breathing dangerous in water?

Hyperventilation lowers carbon dioxide, which delays the urge to breathe during a breath hold. People can lose consciousness from oxygen depletion before they feel the need to inhale, and underwater that means inhaling water. Case reports and news accounts document shallow-water blackout deaths in pools, bathtubs and open water. Breathing in water is not part of the method.

Does the Wim Hof Method boost the immune system?

Not in the way it is often claimed. The study showed a blunted inflammatory response to an inert fragment of dead bacteria over the short term. It did not test live bacteria, viruses or infections, so it does not show the method helps the body fight illness.

Who should not practice the Wim Hof Method?

The episode says it is not safe in water, before or while driving, or during pregnancy. People with seizure disorders and certain cardiovascular conditions should not practice it. It can be practiced on land, seated or lying down, and individual responses vary.

What does hyperventilation feel like during the breathing?

Hyperventilation lowers carbon dioxide and produces respiratory alkalosis. In susceptible people this can cause tingling in the hands and feet, light-headedness, tunnel vision and sometimes fainting, which is why position and setting matter so much.

Study cited: Kox M, van Eijk LT, Zwaag J, et al. Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans. Proceedings of the National Academy of Sciences USA. 2014;111(20):7379-7384. https://doi.org/10.1073/pnas.1322174111

Read the full transcript

Auto-generated from the video captions, so expect small errors.

Welcome back to the Breath channel. My name is Jesse and this is decoding breath. Now, here's the short answer to the question, the Wimhof method. It involves rapid deep breathing, breath retention, and cold exposure. And published research shows it can genuinely influence the autonomic nervous system and reduce the inflammatory response to a bacterial endotoxin. at least in the short-term controlled studies. Now, that's actually referenced to the 2014 Cox study in the PNAS, the proceedings of National Academy of Sciences. It's a real finding. But what almost no one covers honestly is the method does carry some real risks, especially the practice of doing breathing in the

water, which is not part of the method. And there's been blackouts. People have had deaths. And most of the popular health claims that have been made go far beyond what the research actually shows. So full disclosure, I was a certified Wimhof method instructor from 2016 to 2022. I've trained thousands of people in this method over those six years. So stay with me because I want to have a few minutes to show you what the research actually supports, what it doesn't, and the specific safety warnings that sometimes get glossed over on social media and they shouldn't. So this is decoding breath. We try to translate peer-reviewed

breathing research into mechanism and limits and we try to avoid specific protocols. We're saying this is the one. Today we're talking about the Wimhof method. It has three components. Breathing typically 30 to 40 deep breaths. There's a retention. There's a recovery. There's uh cold exposure, ice baths, cold immersion, all those good things. And the commitment or the mindset element, the mental component. uh sometimes it gets sort of glossed over and it's a little bit vague. Most of the online conversation collapses all three of them into just breathing or just cold which is a mistake because the research actually involves a combination of all three. So

let's start with what the research actually does show. The most cited study is the Cox at all study and that was published in the PNAS the proceedings of the National Academy of Sciences and that was in 2014. 12 trained Wimhof practitioners plus 12 controls were injected with a bacterial endotoxin. So it's a component of E. coli that provokes a standardized inflammation response. The train group using the breathing method during the endotoxin exposure, they showed significantly elevated epinephrine levels, sometimes we call that adrenaline, reduced pro-inflammatory cytoines and fewer flu-l like symptoms compared to the controls. This was the first study to show humans could voluntarily influence

the innate immune response which had previously been considered involuntary. That's legitimate. That's huge. That's an important finding. But before we go any further, I do want to slow down and clarify what an endotoxin actually is. Because this is where more misunderstanding lives than almost anywhere else in the breath work conversation. An endotoxin isn't a live bacterium. It's not a live virus. It's not an active infection of any kind. Specifically, the endotoxin used in the Cox study was a purified fragment of the outer membrane of a dead E.coli bacteria. So, it's a molecule called a lipopolysaccharide or LPS. It's chemically inert. It can't replicate. It can't

cause a real infection. What it does trigger is the immune system's alarm response because the immune system recognize LPS as a signature of a Graham negative bacteria and it responds accordingly. Researchers use it precisely because it produces that standardized predictable inflammatory response without the risk of a real life pathogen. So when the Cox study showed that trained Wimhof practitioners had reduced pro-inflammatory cytoines and had fewer flu-l like symptoms after the LPS injection. What it actually demonstrated is that the practice can modulate the body's inflammatory alarm system in response to a specific bacterial signal. That's a real and important finding. What it didn't demonstrate and what

gets misrepresented consistently online is that Wimhof method kills bacteria or fights off a viral infection or cures autoimmune disease. There was no live pathogen in that study. There was no viral exposure. There was no infection to fight. There was a controlled inflammatory stimulus and the trained group blunted the response to it. Those are very different claims and conflating them is one of the most common errors in popular breath work content. This distinction matters because a lot of people have taken this one study and extrapolated into claims that Wimhof method will help them recover from colds faster or fight cancer or manage autoimmune conditions. The study

doesn't support those claims. It supports the narrower claim that the voluntary autonomic activation can modulate the innate immune response to a specific inflammatory stimulus in the short term. Everything beyond that is speculation. It's some of it's plausible, but most of it is running well ahead of the data. Now, here's what happened next, and this is the part that almost always gets left out. So the 2014 Cox study didn't isolate the breathing from the other components. Participants were trained in the full method. So they arrived with cold exposure breathing and mindset practices really all baked together. That means the study tells us something happened. It doesn't

tell us which ingredient did the most work. But then there was a follow-up study and it was published by the same lab in 2020. This went into exactly that question. They took the three pillars apart and they tested them more carefully and the finding matters. So I want to say it really clearly. The effect of the sympathetic activation and the anti-inflammation effect appear to be driven mostly by the cyclical hyperventilation phase of the breathing and the physiological stress response it produces. it didn't seem to be so dependent on the synergy of the three pillars combined. Now, we're going to think about that for a minute

because it changes the story that most people tell about the method. The reason the train group in the original study showed a blunted inflammatory response wasn't likely the proprietary combination. It was likely traceable to that specific physiological event of voluntary hyperventilation triggering a large adrenaline surge which in turn dampened the innate immune response to the endotoxin. In principle, other practices that produce a comparable adrenaline response might produce a comparable effect. They just need to be researched. Intense exercise maybe um certain over breathing protocols. So it could be that if we've studied extreme exercise or other breathing protocols, they could do the same thing when they

involve hyperventilation. It could be that acute cold stress might do it as well, but they were studied as they were doing the hyperventilation. The methods effects appears to be a specific instance of a more general physiological mechanism, not necessarily a unique biological signature. This matters for two reasons. First, it means the honest way to describe the science is to say that voluntary cyclical hyperventilation can acutely modulate the inflammatory response through a catakolamine release. That's a legitimate finding and it's specific. Second, it means we should be skeptical when people claim that Wimhof method is doing something no other practice can do. The current best evidence suggests

the active ingredient is the hyperventilationdriven stress response, which is why there are safety concerns that we're about to discuss that matter a lot. The same physiological event that produces the measurable effects is also the same event that causes people to lose consciousness if they do it in water. Now, let's talk safety because this is where sometimes online content gets a little careless. The Wimhof breathing method involves cyclical hyperventilation. Physiologically, hyperventilation lowers CO2 and produces respiratory alkalossis. In predictable individuals, this causes tingling in the extremities, lightadedness, tunnel vision, and it can cause fainting. When fainting happens on a couch or on the floor, it's no big

deal. But when it happens when you're driving or when you are swimming, that can kill you. This isn't theoretical. Multiple case reports and news accounts have documented shallow water blackout deaths in people who claimed they were practicing the Wimhof method in swimming pools, bathtubs, or open water. The mechanism is well understood. hyperventilation before breath hold delays the CO2 buildup that normally triggers the urge to breathe. So people can hold their breath for much longer. The problem is they lose consciousness from oxygen depletion and they do this before they feel the urge to inhale. So underwater they inhale the water and they drowned. So every reputable

Wimhof instructor teaches this warning. Not every online thing does. So be careful. I just want to make it very clear that this is not the standard Wimhof protocol that people learn when they go to a Wimhof workshop. And so there's been a lot of a lot of things go around in the past few years about this. This is not something that any reputable Wimhof instructor is going to tell you to do. They're going to tell you the exact opposite. But people, would you believe it? Sometimes people do stupid things. That's that's the science. That's that's well researched. I think we have thousands of years of

evidence for this. Now, here's the part that separates the honest research picture from the marketing. The published research on the Wimhof method supports several specific effects. Short-term modulation of the innate immune response to a specific stressor, the endotoxin. Increased plasma epinephrine during the breathing. subjective improvements in mood and in stress in some studies increased brown fat activity in trained practitioners which is likely more attributable to the cold exposure than to the breathing. What the research doesn't support at the same level of evidence despite what popular claims might be going around includes reliable long-term autoimmune disease treatment, cure for depression or PTSD, dramatic longevity effects from

the method itself, or superiority to standard exercise for cardiovascular fitness. Some of these are being studied and might turn out to be true. Right now, they're ahead of the evidence. So, the honest evidencebased answer to the question of the Wimhof method, is it safe? It can be safe when practiced correctly on land, seated or lying down. Go find a Wimhof instructor. They'll help you out. Never before driving. Never while driving. It isn't safe when practicing water. It isn't safe if you're pregnant. And certain people with cardiovascular conditions should not do it. If you suffer from seizure disorders, you should not be practicing Wimhof method. Individual

responses can also vary. And does it do what people claim it to do? Well, the answer is layered. It doesn't produce measurable acute physiological changes. It has one landmark study showing voluntary influence on immune response. And the other popular claims of chronic health outcomes in most cases run ahead of actual research. So if you take one thing away from this, the Wimhof method is a real practice with real acute physiological effects backed by published research. It also has real safety limits that get downplayed in a lot of online content. And we should treat it as a tool, not a specific mechanism or a magic bullet.

You never do it near water. You never do it when you're driving. So here's my question for you, and I want you to drop it in the comments below. If you've tried Wimhof method, what did you actually notice? Not what you expected to notice, but what did you actually observe in your body, in your mood? So, honest reports help other viewers. So, if you want the primary studies I'm referencing plus the deeper breakdown, take a look at the links below. Um, you can also join our free community on Circle. There's a link in the description. It's free to join and it's where ongoing conversations continue.

So, we are looking forward to seeing you next week. Thanks so much for sticking around for this deep dive. And uh what do you want to know? What else would you like us to research for you on this program? We're happy to do it. Put it in the comments below. Thanks again for watching. We'll see you next week.